Oncol Case Rep J | Volume 2, Issue 1 | Short Communication | Open Access
Aya Nakaya*, Shinya Fujita, Atsushi Satake, Takahisa Nakanishi, Yoshiko Azuma, Yukie Tsubokura, Ryo Saito, Akiko Konishi, Masaaki Hotta, Hideaki Yoshimura, Kazuyoshi Ishii, Tomoki Ito and Shosaku Nomura
Department of Internal Medicine, Kansai Medical University, Japan
*Correspondance to: Aya Nakaya
Fulltext PDFBackground: Intravascular Large B-cell Lymphoma (IVLBCL) is a rare lymphoma.
Methods: We retrospectively analyzed six patients with IVLBCL in Japan.
Results: Hemophagocytic syndrome was seen in 4/6 patients, splenomegaly in 5/6 patients, and all patients had B symptoms. The diagnostic site was the bone marrow in 5/6 patients, and patients were found to have a complex karyotype. Four patients had a chromosome 1 abnormality and three had chromosome 11 and 21 abnormalities. Median survival was 11.9 months.
Conclusion: A bone marrow exam might be more useful in detecting IVLBCL than a random skin biopsy in Asian variants.
Chromosome abnormalities; Intravascular Large B-cell Lymphoma; Hemophagocytic
Nakaya A, Fujita S, Satake A, Nakanishi T, Azuma Y, Tsubokura Y, et al. Intravascular Large B-Cell Lymphoma; Our Experience with the Disease at Two Medical Centers. Oncol Case Report J. 2019;2(2):1015..