Oncol Case Rep J | Volume 2, Issue 1 | Case Report | Open Access

Subcutaneous Metastasis of Cancer of the Endometrium: Case Report

Sahara Shurie¹, Luhumyo Loice¹, Odongo Benjamin Elly¹, Emmanuel Wekesa Wamalwa^2*, Oyiengo Vincent¹, Keitany Kibor Kibet³, Orang’o Elkanah Omenge¹ and Muliro Hellen⁴

¹Department of Reproductive Health, Moi University, School of Medicine, Kenya
²Department of Human Pathology, Egerton University, Kenya
³Moi Teaching and Referral Hospital, Kenya
⁴AMPATH Oncology Institute, Kenya

^*Correspondance to: Emmanuel Wekesa Wamalwa 

Fulltext PDF

Abstract

Background: Cancer of the endometrium is the third most common gynecological cancer after cancer of the cervix and cancer of the ovary in Kenya. It is the most common gynecologic malignancy in the United States. The most common endometrial cancer type is endometrioid adenocarcinoma. It is mostly confined to the uterus and less aggressive. The natural history of epithelial corpus cancer includes 4 potential routes of metastasis: contiguous extension, hematogenous dissemination, lymphatic embolization, and exfoliation with intraperitoneal spread. Case
Presentation: A 45-year-old female, Para 5 + 0, presented to our gynecologic oncology clinic in July 2017. The patient was referred from a peripheral health facility for chemotherapy following radical hysterectomy in May 2017 for endometrial cancer. Histology results of the specimen taken during surgery showed endometrial Ca stage 2, grade 3. The patient developed a swelling on the right leg after completion of 6 cycles of Carboplatin and Paclitaxel. The swelling was progressively increasing in size; reaching 7 cm over a period of 6 months. Biopsy specimen was taken from the swelling and histology showed features consistent with metastatic endometrioid adenocarcinoma.
Conclusion: This is a rare occurrence of distant metastasis of cancer of the endometrium. We recommend histologic evaluation of subcutaneous masses developing in patients with advanced endometrial cancer

Citation:

Shurie S, Loice L, Elly OB, Wamalwa EW, Vincent O, Kibet KK, et al. Subcutaneous Metastasis of Cancer of the Endometrium: Case Report. Oncol Case Report J. 2019;2(1):1008.