Nerli RB1,2*, Ghagane SC3, Deole S1, Hiremath MB4 and Dixit NS3
1Department of Urology, JN Medical College, KLE Academy of Higher Education & Research, India
2KLES Kidney Foundation, KLES Dr Prabhakar Kore Hospital & MRC, India
3Department of Urology, KLES Kidney Foundation, KLES Dr Prabhakar Kore Hospital & MRC, India
4Department of Biotechnology and Microbiology, Karnatak University, India
Intratubular Germ Cell Neoplasia (ITGCN) is the precursor lesion for invasive testicular germ cell tumors of adolescents and young adults. ITGCN is diagnosed by testicular biopsy, and has an appearance similar to that of seminoma. The abnormal germ cells are larger than normal spermatogonia, have large hyper-chromatic nuclei with prominent nucleoli, and contain abundant cytoplasm with conspicuous cell borders. Orchiectomy is the main treatment approach in those with unilateral ITGCN and a contralateral normal testicle; those with an atrophic, poorly functioning testis; and those with oligospermia and ITGCN who are pursuing assisted reproductive techniques. In patients with a solitary testicle, treatment for ITGCN needs to be weighed against the resultant infertility and dependence on exogenous testosterone following orchiectomy. We report a case of a 43 year old male presenting with a right sided testicular swelling, which was diagnosed to be Intratubular germ cell tumor on histopathological examination.
Intratubular germ cell neoplasia; Testicular intraepithelial neoplasia
Nerli RB, Ghagane SC, Deole S, Hiremath MB, Dixit NS. Intratubular Germ Cell Neoplasia: A Case Report in a 43 Year Old Male. Oncol Case Report J. 2018;1(1):1007.