J Neurosci Cogn Stud | Volume 2, Issue 2 | Review Article | Open Access

Brain Tumor Stem Cells and New Therapeutic Options

Tolga Turan Dundar*

Department of Neurosurgery, Bezmialem Vakif University, Turkey

*Correspondance to: Tolga Turan Dundar 

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Abstract

Glioblastoma multiforme is a type of aggressive malign brain tumor that is resistant to treatment. Standard treatment consists of surgical resection, radiotherapy and chemotherapy. Despite all effective treatment combinations, the average survival time is under 15 months. Thus, more effective treatment goals are needed. The terms glioblastoma multiforme stem cell, cancer stem cell and brain tumor stem cell are used interchangeably. These cells are responsible for resistance to both radiotheraphy and chemotherapy, tumor recurrence and the heterogenous tumor structure. In the near future, genetical, epigenetical and molecular factors concerning tumor stem cells, the microenvironmental atmosphere and the immune system response to these will be constituting the larger part of brain tumor treatment studies. In this compilation, we aimed at presenting current information about brain tumor stem cells as well as new treatment options.

Citation:

Dundar TT. Brain Tumor Stem Cells and New Therapeutic Options. J Neurosci Cogn Stud. 2018; 2(2): 1011.

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