J Neurol Neurosurg Spine | Volume 4, Issue 1 | Review Article | Open Access

Intra-Cerebrospinal Fluid Chemotherapy is New direction in Pediatric Solid Tumors with Leptomeningeal Metastasis

Abdolkarimi Babak1 , Soheila Zareifar2 *, Salajegheh Pouria3 and Mahdi Shahriari2

1Department of Pediatrics, Lorestan University of Medical Sciences, Iran 2Department of Pediatrics, Shiraz University of Medical Sciences, Iran 3Department of Pediatrics, Kerman University of Medical Sciences, Iran

*Correspondance to: Soheila Zareifar 

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Abstract

Introduction: Intra-Cerebrospinal Fluid (CSF) chemotherapy defines as chemotherapy drugs administration in the brain/spine fluid compartment which can be used for leptomeningeal metastases in infiltrative tumors consisting of leukemia and lymphoma. Material and Methods: We search via the internet, using the online medical database "Pubmed" and the more generic search-engine "Google Scholar”. Results: Collection, spanning over 20 years, was searched, as were recent issues of journals in which articles on the subject are most often found, were original articles. Conclusion: We introduce several intra-CSF chemotherapy regimens in solid tumors

Keywords:

Intrathecal chemotherapy; Leptomeningeal metastasis; Pediatric; Brain tumor

Citation:

Babak A, Zareifar S, Pouria S, Shahriari M. Intra-Cerebrospinal Fluid Chemotherapy is New direction in Pediatric Solid Tumors with Leptomeningeal Metastasis. J Neurol Neurosurg Spine. 2019; 4(1): 1016..

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