J Gynecol Oncol | Volume 4, Issue 2 | Research Article | Open Access

Recurrent Struma Ovarii with Incidental Peritoneal Inclusion Cysts: A Potential Pitfall

Trihia HJ1*, Korfias D2, Souka E1, Fotiou A2, Karelis L1 and Vorgias G2

1Department of Pathology, ‘Metaxas’ Memorial Cancer Hospital, Greece
2Department of Gynecologic Surgical Oncology, ‘Metaxas’ Memorial Cancer Hospital, Greece

*Correspondance to: Helen J Trihia 

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Objective: Peritoneal Inclusion Cysts (PICs) is the formation of multicystic abdominal masses. They are associated with previous abdominal surgery. Struma ovarii can be accompanied by ascites and raised CA-125. We present a case of recurrent struma ovarii, associated with incidental PICs. Methods: A 22 year-old woman was admitted to our hospital with ascites. She was diagnosed with a right ovarian mass and raised CA-125 (2761.3 U/ml). Her surgical history included a prior laparoscopic cystectomy, for struma ovarii, with preservation of the right ovary. The association of pelvic mass, ascites and elevated CA-125, was highly suspicious of malignancy. The woman underwent right salpingo-oophorectomy. Results: At operation, numerous cystic structures were incidentally found. The ovarian mass was a pure struma ovarii. Pathological examination of the cystic structures was consistent with PICs. Conclusion: PICs are rare cystic structures that arise from the abdominal peritoneum and can mimic gynecologic malignancies. Past histological diagnosis should always be reviewed. CA-125 can be elevated in both benign and malignant ovarian tumors, including struma ovarii. The co-existence of a second pathology, not diagnosed preoperatively, like PICs should be borne in mind in cases of ascites after previous surgery.


Struma ovarii; Recurrence; Benign cystic mesothelioma; Peritoneal inclusion cysts; CA-125; Pseudo-Meig’s syndrome


Trihia HJ, Korfias D, Souka E, Fotiou A, Karelis L, Vorgias G. Recurrent Struma Ovarii with Incidental Peritoneal Inclusion Cysts: A Potential Pitfall. J Gynecol Oncol. 2021; 4(2): 1054.

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