J Gynecol Oncol | Volume 3, Issue 6 | Research Article | Open Access

Safety and Acceptance of HPV Vaccine: A Hospital - Based Survey at Tertiary Care Centre

Verma ML*, Singh U, Rai P, Sachan R and Sankhwar PL

Department of Obstetrics and Gynecology, King George's Medical University, India

*Correspondance to: Manju Lata Verma 

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Objective: If really safety of HPV vaccines is the concern for non-acceptability for HPV vaccines in northern India or there are some other obstacles. This was the question. So study was done to evaluate the safety of HPV vaccines in individuals who have accepted it and also to assess the factors responsible for low acceptance for vaccine. Material and Methods: A pilot intervention study was done from June 2016 to June 2017 in the Department of Obstetrics and Gynecology of King George Medical University, Lucknow, Uttar Pradesh, India. First acceptability was determined by filling questionnaire by taking face to face interview and subjects who accepted for the vaccines, were provided vaccines (Cervarix). Various side effects in terms of pain at injection site, erythema, induration, fever, myalgia etc. were assessed after every injection. The study was ethically approved from the Institutional Ethical Committee of the KGMU, Lucknow, Uttar Pradesh, India (1689/Ethics/R cell/17). Mean with standard deviation was used for continuous variables. Frequencies and percentages were noted for categorical variables. Results: Face to face interviewers were taken for 302 cases. Out of these 302, amongst 70 cases showed acceptability (23%). Total Cervarix doses given were 196. Most common side effect was pain at injection site followed by induration 3.5% and 1.5% respectively. Conclusion: HPV vaccines are quite safe and safety is not a major concern for non-acceptability of HPV vaccines.


Carcinoma cervix; Cervarix; Gardasil; HPV vaccine


Verma ML, Singh U, Rai P, Sachan R, Sankhwar PL. Safety and Acceptance of HPV Vaccine: A Hospital - Based Survey at Tertiary Care Centre. J Gynecol Oncol. 2020; 3(6): 1047.

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