J Gastroenterol Hepatol Endosc | Volume 5, Issue 1 | Case Report | Open Access
Yin-Mei Fu, Chao-Chao Chen, Yi-Yao Chen, Fu-Jin Liu and Cheng Lan*
Department of Gastroenterology and Hepatology, Hainan Medical University, Hainan General Hospital, China
*Correspondance to: Fu-Jin Liu and Cheng Lan
Fulltext PDFWe report a very rare case of primary Mucosa Associated Lymphoid Tissue (MALT) lymphoma of
the esophagus. A mild-life man was referred to our hospital for further examination and treatment
of oesophageal tumor. Although a physical examination and laboratory data showed no significant
abnormalities, endoscopic observation revealed slightly elevated submucosal tumour-like lesions in
the oesophagus, and CT show esophageal cancer mainly. However tissue lesions were composed of
diffuse small atypical lymphoid cells that is, centrocyte like cells-which were stained with positive
for CD20, CD19,CD43 MUM-1 and Bcl-2, and negative for CD3, CD5, CD10, Bcl-6, and cyclin D1.
Therefore it was diagnosed as mucosa associated lymphoid tissue lymphoma of the oesophagus. For
treatment, it is helpless by eradication of H. pylori, but useful by chemotherapy by R-CHOP.
Lymphoma arises not only from lymphoid tissue, such as in the tonsil or Peyer’s patches, but also
from the stomach that normally contains no lymphoid tissue. Extranodal lymphoma occurs most
commonly in the gastrointestinal tract, which accounts up to 5% to 20% of all cases [1]. MucosaAssociated Lymphoid Tissue (MALT) lymphoma is a subtype of extranodal lymphoma [2]. It is
reported that MALT lymphomas occurring usually in other parts of the gastrointestinal tract, such
as the gastric, duodenum, ileum, and colon, but infrequently in the oesophagus [3,4]. Here we report
a rare case of MALT lymphoma in the oesophagus.
Fu Y-M, Chen C-C, Chen Y-Y, Liu F-J, Lan C. A Rare Case of Mucosa Associated Lymphoid Tissue (MALT) Lymphoma in the Esophagus. J Gastroenterol Hepatol Endosc. 2020;5(1):1079..