J Clin Ophthalmol Eye Disord | Volume 2, Issue 1 | Case Report | Open Access

Visual Disturbance as Presenting Feature and Macular Hole as Complication of Chronic Myeloid Leukemia

Rahul Bhargava^1* and Prachi Kumar²

¹Department of Ophthalmology, School of Medical Sciences & Research, Sharda University, India
²Department of Pathology, School of Medical Sciences & Research, Sharda University, India

^*Correspondance to: Rahul Bhargava 

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Abstract

A 42-year old male presented with diminution of vision in left eye, weakness, and lethargy. On fundus examination (with +90 D lens), there was paramacular thickening with central macular and peripheral hemorrhages in left eye. Macular thickening was confirmed by Optical Coherence Tonography (OCT). Blood film demonstrated leukocytes are with the presence of precursor cells of the myeloid lineage. Fluorescence in Situ Hybridization (FISH) revealed the presence of Philadelphia chromosome in 48% of inter phase cells studied. Patient was put on treatment with Imatinib tablet 400mg twice daily and treatment monitored. In the treatment phase, lamellar macular hole developed in the left eye at nine months. This case is being reported because of its unusual presentation and complication (Lamellar Macular Hole).

Keywords:

Chronic myeloid leukemia; Lamellar macular hole; Visual disturbance

Citation:

Bhargava R, Kumar P. Visual Disturbance as Presenting Feature and Macular Hole as Complication of Chronic Myeloid Leukemia. J Clin Ophthalmol Eye Disord. 2018; 2(1): 1021.