J Clin Obstet Gynecol Infertil | Volume 2, Issue 1 | Research Article | Open Access
Ahmed M. Bahaa Eldin*
Department of Obstetrics and Gynecology, Ain Shams University, Egypt
*Correspondance to: Ahmed M. Bahaa Eldin
Fulltext PDFBackground: Negotiation between the embryo and endometrium in addition to endometrial receptivity is mainly hpothesized as the two main molecular and cellular factors involved in the process of implantation.
Aim: To study and explore the effect of local endometrial scratching, hydrotubation and saline infusion on IVF outcome after failed one past IVF trial. Study
Design: A prospective, randomized, control trial. Setting: Banoon IVF Center. Patients and methods: A total of 800 women either with unexplained or with mild male factor infertility were divided randomly into four groups. In hydrotubation group 200 women, endometrial scratching group, 200 women and in saline infusion group, 200women, control group 200 women no intervention has been made. For every study category, folliculometry started at cycle day 7 at oocyte retrieval day endometrial scratching have been made in one study category, saline infusion in another study category, hydrotubation in the third study category and no intervention in the fourth study category.
Results: The live birth rates were statistically significantly greater in the hydrotubation, endometrial scratching and saline infusion study subjects compared to the control group (p-values 0.001, 0.001, 0.036 respectively).
Conclusion: Hydrotubation, Endometrial scratching and intra uterine saline infusion are useful in increasing biochemical, clinical and live birth rates after failed previous IVF trials.
Bahaa Eldin AM. Physical Endometrial Handling after Failed IVF and Cycle Outcome. J Clin Obstet Gynecol Infertil. 2017; 2(1): 1029.