J Clin Obstet Gynecol Infertil | Volume 1, Issue 5 | Case Report | Open Access

Hidradenitis Suppurativa: The Third Cause of Vulva Carcinoma

Ineke Janse^1*, Gilles Diercks^1,2, Jan Doff², Marian Mourits³ and Barbara Horvath¹

¹Departments of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
²Departments of Pathology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
³Departments of Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

^*Correspondance to: Ineke Janse 

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Abstract

The development of Squamous Cell Carcinoma (SCC) is a severe complication of chronic Hidradenitis Suppurativa (HS). Male patients with prolonged HS in extra-axillary areas are especially at risk of this complication. The case in our paper of HS associated with vulvar SCC emphasizes that women can also develop this complication. In addition to lichen sclerosus vulvae (via dVIN) and high risk HPV (via uVIN) there is a third disease that can lead to vulvar cancer, namely chronic HS. The clinician should look out for a malignant transformation in the presence of severe, chronic HS, and have a low threshold for biopsy. Staging, therapy and follow-up should be performed by gynecologic oncologists.

Keywords:

Chronic hidradenitis suppurativa; Sclerosus vulvae; Vulvar cancer

Citation:

Janse I, Diercks G, Doff J, Mourits M, Horvath B. Hidradenitis Suppurativa: The Third Cause of Vulva Carcinoma. J Clin Obstet Gynecol Infertil. 2017; 1(5): 1022.