J Clin Obstet Gynecol Infertil | Volume 1, Issue 3 | Research Article | Open Access
Ayman Shehata Dawood1*, Mohamed A. Elsharawy1 and Amr El-Badry2
1 Department of Obstetrics and Gynecology, Tanta University, Egypt
2 Department of Radiology, Tanta University, Egypt
*Correspondance to: Ayman Shehata Dawood
Fulltext PDFObjective: To assess uterine perfusion early in pregnancy in women with hypovitaminosis D3 and evaluate if findings are linked to poor pregnancy outcomes. Patients and
Methods: 300 primigravidae with a singleton pregnancy (11weeks to13weeks) were included in this study attending for routine antenatal care at Tanta University Hospitals. Vitamin D3 levels were estimated plus transvaginal color Doppler ultrasound to measure the pulsatility index of the uterine arteries and the spiral arteries.
Results: The mean age of enrolled patients was 26.2±4.593 years, mean BMI was 27.64 ± 3.348 and the mean gestational age at booking was 8.54±1.72 weeks. Hundred and fourteen cases out of 300 cases (38%) had hypovitaminosis D3. The cases with hypoperfusion (43 cases) were complicated by spontaneous abortion (3 cases), preterm labor (4 cases), IUFD (4 cases), hypertension (17 cases), IUGR (7 cases), placental abruption (2 cases). Cases with hypovitaminosis only and normal perfusion were not linked to poor outcomes where only 3 cases suffered late preterm labour after 34 weeks with good neonatal outcomes.
Conclusion: Early uterine hypoperfusion in hypovitaminosis D3 had positive predictive factor in relation to poor pregnancy outcomes while deficiency of Vitamin D only was not related to poor pregnancy outcomes.
Uterine artery doppler; Uterine perfusion; Vitamin D3; Pregnancy outcome
Dawood AS, Elsharawy MA, El- Badry A. Early Uterine Perfusion Assessment in Selected Population with Hypovitaminosis D3: Which Factor is Predictive for Poor Pregnancy Outcome? J Clin Obstet Gynecol Infertil. 2017; 1(3): 1015.