J Clin Obstet Gynecol Infertil | Volume 1, Issue 1 | Research Article | Open Access
Morgana Trindade-Pacheco1, Álvaro Antônio Borba2, Andrea Teixeira Cadaval-Gonçalves2, Cláudio Galleano Zettler3, Gustavo Py-Gomes-da-Silveira3 and Patrícia El-Beitune3*
1Department of Adiology, Federal University of Health Sciences of Porto Alegre (UFSCPA), Brazil
2Department of Radiology, Breast Imaging Diagnosis Experts, UFSCPA, Brazil
3Department of Gynecology and Obstetrics, UFCSPA, Brazil
*Correspondance to: Patrícia El-Beitune
Fulltext PDFBreast cancer presents great heterogeneity in its findings. We aim to analyze suspicious breast nodules by echographic study for breast cancer, evaluating the accuracy and inter-observer agreement in the BI-RADS 4A, 4B, 4C, and 5 classifications. Of the 70 patients selected for a prospective study, 40 confirmed positive for malignancy. Among the various ranges of classification for category 4, no patient classified with category 4A nodules showed malignancy, 28.6% showed for category 4B, and 75.0% and 96.3% for categories 4C and 5, respectively. The agreement rates resulted in the Kappa of 0.896. Area under the curve for BI-RADS categories was 0.939 (CI 95%, 0.85 to 0.98), p=0.0001. Category 4C was the best accuracy point, with sensitivity 92.5% and specificity 83.3%. Category 4C was characterized as having higher accuracy for breast cancer diagnosis, having shown good agreement among different researchers when the objective criteria were meticulously applied.
Mammary nodules; Breast cancer; Ultrasound; BI-RADS; Subcategory 4
Trindade-Pacheco M, Borba ÁA, Cadaval-Gonçalves AT, Zettler CG, Py-Gomes-da-Silveira G, El-Beitune P. Features Delimitation using Bi-RADS System for Ultrasound to Evaluate the Accuracy for Subcategory 4 and Category 5 in the Diagnosis of Breast Nodules – Analysis of a Preliminary Study. J Clin Obstet Gynecol Infertil. 2016; 1(1): 1003.