Int J Family Med Prim Care | Volume 1, Issue 6 | Case Report | Open Access

A Unique Case of Gastroparesis Vs. Functional Dyspepsia: The Role of Buspirone

Sadiku M1 , Rodriguez C1 and Veltri KT1,2*

1Touro College of Pharmacy, New York, USA 2 Montefiore Medical Center, Bronx, New York, USA

*Correspondance to: Veltri KT 

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Abstract

Gastroparesis is a chronic disorder of the stomach characterized by delayed emptying without evidence of mechanical obstruction. Gastroparesis is identified in clinical practice through the recognition of these clinical symptoms and confirmative diagnosis of delayed gastric emptying. Buspirone is the first of a class of selective serotonin-5-HT1A receptor partial agonists indicated for the management of anxiety. It also has some effect on dopamine-D2 autoreceptors and, like antidepressants, can down-regulate β-adrenergic receptors. Newly defined interests in the pathophysiology behind gastroparesis provide promise for a new era of treatment options including buspirone. The rationale for using buspirone in the treatment of gastroparesis and FD is secondary to impaired gastric accommodation.

Keywords:

Gastroparesis; Functional dyspepsia; Postprandial distress syndrome; Epigastric pain syndrome

Citation:

Sadiku M, Rodriguez C, Veltri KT. A Unique Case of Gastroparesis Vs. Functional Dyspepsia: The Role of Buspirone. Int J Fam Med Prim Care. 2020; 1(6): 1026.

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