Ann Vasc Med | Volume 3, Issue 1 | Commentary | Open Access

The Below-the-Knee Paclitaxel Angioplasty Meta-Analysis Lacks the Bite of Its Blockbuster Predecessor; Shall We Let Sleeping Dogs Lie for Now?

Shereen XY Soon¹, Charyl JQ Yap¹, Shaun QW Lee¹, Hao Y Yap¹, Jia S Tay², Edward TC Choke², Tze T Chong¹ and Tjun Y Tang^1,3*

¹Department of Vascular Surgery, Singapore General Hospital, Singapore ²Department of General Surgery, Seng Kang General Hospital, Singapore ³Duke-NUS Graduate Medical School, Singapore

^*Correspondance to: Tjun Y Tang 

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Abstract

The recent meta-analysis, published by Katsanos et al. whereby findings of a worse amputation free survival signal, from the use of paclitaxel-coated balloons in the infra-popliteal arteries for treatment of critical limb ischemia, was reported, has once again found itself center-stage in the peripheral endovascular community. However, like all sequels, it does not have the impact of its predecessor. In this article, we examine the limitations of this meta-analysis in comparison to their previous work. For now, the findings of this meta-analysis should not impact anyone’s practice until these issues have been adequately addressed.

Keywords:

Drug-coated balloon; Amputation free survival; Mortality; Paclitaxel; Knee

Citation:

Shereen XY Soon, Charyl JQ Yap, Shaun QW Lee, Hao Y Yap, Edward TC Choke, Tze T Chong, et al. The Below-the-Knee Paclitaxel Angioplasty Meta-Analysis Lacks the Bite of Its Blockbuster Predecessor; Shall We Let Sleeping Dogs Lie for Now?. Ann Vasc Med. 2020; 3(1): 1012..