Ekim Ekinci1, Audrey Scholoff2, Gloria Obi2, Ngoc Vu2, George Carrum2 and Rammurti T Kamble2*
1Department of Pharmacy, Houston Methodist Hospital, USA
2Department of Cell and Gene Therapy, Baylor College of Medicine and Houston Methodist Hospital, USA
Posaconazole is a triazole antifungal agent with a broad-spectrum antifungal activity; it is frequently used as prophylaxis and treatment of fungal infections. We here in document the first report of posaconazole-induced uncontrolled hypertension in an allogeneic transplant recipient, and provide a brief review of such reports in the literature. Recognition of this phenomenon led to a dramatic decrease in the number and dose of antihypertensive medications needed, and facilitated optimum blood pressure control in our patient.
Azole; Posaconazole; Hypertension
Ekinci E, Scholoff A, Obi G, Vu N, Carrum G, Kamble RT. PosaconazoleInduced Uncontrolled Hypertension in Allogeneic Hematopoietic Transplant. Ann Stem Cell Res Ther. 2018; 2(3): 1019.