Ann Short Rep | Volume 3, Issue 2 | Research Article | Open Access

Gynec-Onco-Registry of a Tertiary Center of North India

Bhardwaj B* and Gunjan R

Department of Obstetrics and Gynecology, Armed Forces Medical College, India

*Correspondance to: Bikram Bhardwaj 

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Abstract

Background: In the recent years there has been a surge in incidence of cancers globally. Not only the incidence of cancers even the case fatality rate due to malignancies is on the rise in last few years. Gynecological malignancies are one among the commonest malignancies affecting the life of women worldwide. Keeping in view these rising trends, this study was undertaken to see the patterns of various gynecological cancers in this tertiary center of Armed Forces of India. Materials and Methods: This is a prospective observational study of patients with gynecological cancers who visited the gynec-oncology OPD of a Tertiary Care Hospital of Armed Forces of India from January 2018 to January 2020 for treatment at this center. In all cases with gynecological cancers, a detailed history taking followed by clinical examination was done. Further evaluation with special investigations like USG/CT/MRI, tumor markers and tissue biopsy to establish malignancy was done based on type of malignancy. Depending upon the extent of disease, patients underwent either primary surgery in early disease or were treated with NACT followed by surgery in cases of advanced ovarian/endometrial cancers. Advanced cervical/vulvar/vaginal cancers were treated with chemo-radiation and surgery was reserved for early stage disease. Results: During the entire duration of study, 116 patients were found to have various types of gynecological malignancies at our center. Carcinoma ovary was the most common cancer reported at our center followed by cervix, endometrium, GTN, vulva and vagina. Out of total 47 cases of Carcinoma ovary at our center 20 cases had early disease and underwent primary surgery whereas 24 cases had already advanced disease at admission warranting NACT followed by surgery. Three cases reported with isolated recurrence amenable to surgery post interval cyto-reduction. These patients underwent secondary cyto-reductive surgery Out of 35 cases of carcinoma cervix 15 were operable with early stage disease whereas 20 patients had disseminated disease not amenable to surgery at the time of first visit and were treated with CCRT. Twenty-five patients had Carcinoma Endometrium and only 2 patients had advanced disease at admission warranting NACT followed by surgery. Out of five cases of GTN 4 were managed with single agent chemotherapy and 1 patient had to resort to multi-drug regimen in view of high BHCG levels. Two patients with carcinoma vulva had advanced disease with co-morbidities and underwent chemo-radiation. One patient had advanced carcinoma vagina and underwent CCRT. There were no cases of fallopian tube cancer and sarcoma uterus at our center. One patient had synchronous malignancy with endometroid adenocarcinoma of endometrium and granulosa cell tumor in one of the ovaries. Conclusion: To conclude carcinoma Ovary was the commonest tumor reported at our center though most patients had advanced disease at the time of admission. Majority cases of carcinoma endometrium were early stage and operable. 40% cases of carcinoma cervix were operable and rest underwent CCRT. Incidence of GTN, vulvar and vaginal cancer was quiet less at our center.

Keywords:

Gynecological cancer; Cervical cancer; Ovarian cancer

Citation:

Bhardwaj B, Gunjan R. Gynec-Onco- Registry of a Tertiary Center of North India. Ann Short Reports. 2020; 3: 1052.

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