Ann Plast Reconstr Surg | Volume 4, Issue 4 | Research Article | Open Access

The Use of Acellular Dermal Matrix for Chest Wall Reconstruction: A Systematic Review

François Lescarbotte^1*, Barbara Hersant¹, Raphaëlle Billon^1,2, Koohyar Habibi¹, Oana Hermeziu¹, Jean-Paul Meningaud¹ and Romain Bosc^1,2,3

¹Department of Plastic, Reconstructive, Aesthetic and of Maxillofacial Surgery, Henri-Mondor University Hospital,
France
²Henri Mondor Breast Center, Paris-Est Créteil University, France
³Université Paris-Est Créteil, INSERM, France

^*Correspondance to: François Lescarbotte 

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Abstract

Background: Chest wall reconstruction is required after full-thickness chest wall resection to preserve respiratory function and protect intra thoracic organs. Surgeons now have access to an array of synthetic and biologic prostheses that, together with soft-tissue coverage, restore chest wall integrity. The effectiveness of Acellular Dermal Matrices (ADM) in chest wall reconstruction has not been formally evaluated. To address this issue, we performed a systematic review of studies analyzing complication rates of ADM for chest wall reconstruction.
Materials and Methods: We performed a literature search in the MEDLINE and Cochrane databases from 2000 until June 2020 to identify studies that have analyzed the use of ADM alone. We then extracted relevant data’s from the studies that met the inclusion criteria.
Results: Out of an initial 116 published studies retrieved 20 studies involving 126 patients who underwent chest wall reconstruction with ADM matched our inclusion criteria and were included in the analysis. The total complication rate was 19.0%. The most common complications were local infections 7.1%, postoperative hematoma and seroma 5.5%, followed by few other complications including 2 wound breakdowns, 2 distal flap necrosis without ADM exposure, 2 pleural effusions, 2 postoperative pneumonias and 1 case of Cerebrospinal Fluid (CSF) leak due to dural tear.
Conclusion: ADM appears to be a safe option for reconstructing the chest wall. The array of new products on the market calls for evaluation of their effectiveness in prospective as well as costeffectiveness

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Citation:

Lescarbotte F, Hersant B, Billon R, Habibi K, Hermeziu O, Meningaud J-P, et al. The Use of Acellular Dermal Matrix for Chest Wall Reconstruction: A Systematic Review. Ann Plast Reconstr Surg. 2020;4(4):1064..