Ashwani K Dhingra1*, Bhawna Chopra1 and Brahmaiah Bonthagarala2
1Guru Gobind Singh College of Pharmacy, India
2Hindu College of Pharmacy, India
Background: Although, various synthetic anti-inflammatory drugs were reported to be used for the treatment of inflammatory disorders but it is still a challenge for the medicinal chemists to develop more potent therapeutic agents. Since most of the clinically used anti-inflammatory drugs like NSAIDs, Coxibs, GCs and TNF inhibitors etc. are allied with considerable toxicity.
Method: A variety of medicinal plants are known to exhibit a wide range of interesting biological activities like antioxidant, anti-inflammatory, anticonvulsant, analgesic, antimicrobial, anticancer, antiprotozoal, antioxidant, antiparasitic, antiplatelet, cardioprotective, anthelmintic, antidiabetic, antitubercular, trypanocidal and anti-HIV. Reported literature survey has been studied to summarize medicinal plants which were utilized as potential anti-inflammatory agents.Results: The search of novel anti-inflammatory agent is not an ending process. An array of herbal drugs targeting inflammatory cytokines has been identified in the past regained their popularity due to devoid of toxicity.Conclusion: The present review summarizes recently explored anti-inflammatory herbal drugs and preparations which will be precious for the researchers to working in the field of anti-inflammatory natural chemistry.
Inflammation; Herbal drugs; Anti-inflammatory agents; Phyto-constituents; COX
Dhingra AK, Chopra B, Bonthagarala B. Natural Anti-Inflammatory Agents: Recent Progress and Future Perspectives. Ann Pharmacol Pharm. 2018; 3(5): 1158.