Ann Pharmacol Pharm | Volume 2, Issue 3 | Review Article | Open Access

Comparison of the Effect of Kampo Medicines, Dai- Kenchu-To, Ninjin-To, Keishi-Ninjin-To, and Bishi-Richu- To of Levels of Gut-Regulated Peptides in Human Plasma

Yuhki Sato^* and Hiroki Itoh

Department of Clinical Pharmacy, Oita University Hospital, Japan

^*Correspondance to: Yuhki Sato 

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Abstract

The traditional herbal (Kampo) medicines are empirically used to treat chronic hypofunction of the gastrointestinal tract. But the action mechanism is not well understood. So, we examined the effects of four Kampo medicines on plasma levels of five neuro peptides. We hypothesized that Ninjinto and Bushi-richu-to might promote peristaltic reflex, Dai-kenchu-to, Ninjin-to, Keishi-ninjin-to, and Bushi-richu-to might have gastro protective effect by increase of mucosal blood flow.

Keywords:

Kampo medicine; Gut-regulatory peptide; Mucosal protection; Gastrointestinalmotility

Citation:

Sato Y, Itoh H. Comparison of the Effect of Kampo Medicines, Dai-Kenchu-To, Ninjin-To, Keishi-Ninjin-To, and Bishi- Richu-To of Levels of Gut-Regulated Peptides in Human Plasma. Ann Pharmacol Pharm. 2017; 2(3): 1029.