Ann Orthop Surg Res | Volume 1, Issue 1 | Case Report | Open Access

Central and Peripheral Neurologic During Sjogren's Syndrome

Kawtar Nassar*, Wafae Rachidi, Saadia Janani and Ouafa Mkinsi

Department of Rheumatology, Ibn Rochd University Hospital, Morocco

*Correspondance to: Kawtar Nassar 

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The Sjögren’s syndrome is a frequent exocrinopathy autoimmune (0.5% to 3% prevalence). Furthermore exophthalmia and xerostomia, it can be complicated by extra-glandular systemic manifestations. That’s including neurological complications, which are rare and little known; they may precede or occur simultaneously with the sicca syndrome. The diagnosis of these neurological manifestations is often difficult with a long diagnostic delay. Neurological manifestations encountered can affect the peripheral or central nervous system, the coexistence of the two is rare. We report a patient case, 51 years old, followed since 2003 for goiter treatment. The diagnosis of syndrome Sjogren primitive landed in 2007 according to the criteria of Vitali. Admitted to the rheumatology department for assessment of impaired general condition, dyspnea stages III according to NYHA, a depressive syndrome, extremity paresthesis, and inflammatory polyarthralgia. Electromyogram four members showed a myogenic syndrome lower limb motor and sensory neuropathy and axonal origin. Muscle biopsy was normal at the boundary of the part taken. Brain magnetic resonance imaging performed before the headache and depressive syndrome has objectified hyper intensities signals of the periventricular white matter and subcortical left. The patient received a course of Rituximab, symptomatic treatment of xerophthalmia and xerostomia.


Gougerot sjogren; Neurological complications; Central neuropathy


Nassar K, Rachidi W, Janani S, Mkinsi O. Central and Peripheral Neurologic During Sjogren's Syndrome. Ann Orthop Surg Res. 2018; 1(1): 1001.

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