Ann Med Med Res | Volume 5, Issue 1 | Review Article | Open Access

Characteristics of New Oxygen-Carrying Plasma and Its Application Prospects in the Treatment of Severe Acute Pancreatitis

Jingyu Song1, Xinting Pan2, Junjie Li1, Xiaomin Hu1 and Wen Yin1*

1Department of Emergency Center of Xijing Hospital, Airforce Medical University, Xi'an, China
2Department of Emergency Intensive Care Unit, the Affiliated Hospital of Qingdao University, Qingdao, China

*Correspondance to: Wen Yin 

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Abstract

Oxygen-carrying plasma, a new type of colloid substitute, is composed of Hydroxyethyl Starch
(HES) and acellular Hemoglobin-Based Oxygen Carriers (HBOCs). It can supplement colloidal
osmotic pressure and rapidly improve the body’s oxygen supply. The resuscitation effect of the new
oxygen-carrying plasma in animal shock models is better than that of HES or HBOC alone. It can
reduce the histopathological damage and mortality associated with severe acute pancreatitis, and
it is expected to become an interesting treatment method for severe acute pancreatitis. This article
reviews the characteristics of the new oxygen-carrying plasma, its role in fluid resuscitation, and its
application prospects in the treatment of severe acute pancreatitis.

Keywords:

New oxygen-carrying plasma; Fluid resuscitation; Severe acute pancreatitis; Hydroxyethyl starch; Hemoglobin-based oxygen carriers

Citation:

Song J, Pan X, Li J, Hu X, Yin W. Characteristics of New Oxygen-Carrying Plasma and Its Application Prospects in the Treatment of Severe Acute Pancreatitis. Ann Med MedicalRes. 2022; 5: 1040..

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