Ann Med Med Res | Volume 5, Issue 1 | Research Article | Open Access
Muinah Adenike Fowora1*, Joy Ogunsanya1, Kazeem Adewale Osuolale2, Faustina Uloma Onyeaghasiri3, Adenike Aiyedogbon1 and Bamidele Iwalokun1
1Department of Molecular Biology and Biotechnology, Nigerian Institute of Medical Research, Nigeria 2Monitoring and Evaluation Unit (Biostatistics), Nigerian Institute of Medical Research, Nigeria 3FOWM Biotechnology Laboratories, Nigeria
*Correspondance to: Fowora Muinah Adenike
Fulltext PDFUrine epidemiological surveillance from outpatient clinic patients can provide insights into urinary pathogen prevalence and antibiotic susceptibility. The goal of this study was to find the most common bacterial isolates associated with ASB in women in Lagos, Nigeria. The study also evaluated the antimicrobial susceptibility pattern of the isolated bacteria. Urine samples were collected from women attending the outpatient clinic of the Lagos University Teaching Hospital in Lagos State, Nigeria, who were 18 years or older, did not have symptoms of urinary tract infections, and were not currently on antibiotics. The samples were tested for significant bacteriuria using microscopic methods, and urine culture and urinalysis were performed using a commercial test strip. Antimicrobial susceptibility testing was performed to evaluate the isolated bacteria's antibiotic susceptibility profile. Of the 162 women included in the study, 45 had significant bacteriuria. These women, however, yielded 48 bacterial isolates. The most common urinary pathogen isolated was Staphylococcus aureus, followed by E. coli. All of the bacteria were susceptible to imipenem and nitrofurantoin, but there was significant resistance to ampicillin, augmentin, and tetracycline. The presence of nitrites in the urine was found to be significantly associated with significant bacteriuria, while the presence of leucocytes in the urine was found to be associated with staphylococcal infection. Staphylococci species appear to be the new most common cause of ASB and, by extension, urinary tract infection. Nitrofurantoin and vancomycin are effective treatments for ASB. The use of urinalysis results to establish significant bacteriuria is insufficient.
Asymptomatic bacteriuria; Urinalysis; Bacteria; Antimicrobial susceptibility
Fowora MA, Ogunsanya J, Osuolale KA, Onyeaghasiri FU, Aiyedogbon A, Iwalokun B. Bacteria and Urinalysis Profile of Asymptomatic Bacteriuria in Women in Lagos, Nigeria. Ann Med Medical Res. 2022; 5: 1038..