Research Article

A Predictive Scoring Model for Relapse in Chronic HCV Patients with Rapid Virologic Response to PEG Interferon/Ribavirin Treatment

Background: Chronic hepatitis C is a major health problem in Taiwan, treatment is costly and has multiple side effects, identifying the predictors of relapse of the disease after achieving Rapid Virological Responses (RVR) to PEG Interferon/Ribavirin (PEG-IFN/RBV) treatment will help in better selection of patients and avoidance of unnecessary side effects.

Published 27 Mar, 2019


HCC and DAA: Open Issue or Closed Wrangling?

Since the introduction of Direct-Acting Antiviral Agents (DAAs), the treatment of HCV is radically improved with Sustained Virological Response (SVR) rates exceeding 95%.

Published 28 Jan, 2019

Clinical Image

A Possible Genetic Profile for the Early Detection of HCC among Egyptian Patients with Chronic HCV

Gene expression of biomarkers involved in hepatocarcinogenesis could be used for the early diagnosis of Hepatocellular Carcinoma (HCC).

Published 08 Jan, 2019

Research Article

Small Bowel Capsule Endoscopy in Crohn’s Disease and Controls: Upper Lesions, Impact and Transit Times in a Tertiary Referral Center

Background and Aims: The role of Small Bowel Capsule Endoscopy (SBCE) in Crohn’s Disease (CD) is debated.

Published 28 Sep, 2018

Review Article

Update on Clostridium difficile Infection in Patients with Solid Organ Transplantation

Clostridium difficile Infections (CDI) is increasing in recipients of Solid Organ Transplant (SOT).

Published 20 Aug, 2018

Case Report

Concurrent Devascularization and Splenectomy versus Splenectomy alone in Patients with Hypersplenism but Silent Esophageal Varices

Background: Bleeding esophageal varices is a catastrophic event with high mortality; every effort should be exerted to prevent such a consequence.

Published 18 Jul, 2018

Case Report

Myelofibrosis Diagnosed Through the Explant Liver Way!

Cryptogenic Chronic Liver Disease (CLD) remain an important cause of chronic liver disease where no etiological inciting agent could be attributed to causation of disease, with recent advances in diagnostic testing the prevalence of cryptogenic CLD have decreased though not completely eliminated.

Published 17 Jul, 2018

Case Series

Sigmoid Esophagus in Systemic Sclerosis: A Case series

The hallmark feature of esophageal involvement in Systemic sclerosis is absent peristalsis or ineffective esophageal motility [1].

Published 25 Jun, 2018

Research Article

Zingiber officinale and Piper nigrum Consumption as Aphrodisiacs on Viscerals and Testis of Male Wistar Rats

The use of these substances otherwise known as aphrodisiacs with capacities to arouse or increase sexual drive or libido and the increasing incidence of male sexual dysfunction is necessitating more and rapid search into plants with aphrodisiacs potentials.

Published 30 Mar, 2018

Case Report

Viral Load during the First Month of Direct-Acting Antivirals or Interferon Plus Ribavirin for Hepatitis C Infection

Background/Aims: A rapid decrease in liver inflammation following hepatitis C resolution can account for hepatocellular carcinoma recurrence.

Published 26 May, 2018

Research Article

Statin Use is Associated with Reduction in Fibrosis and Cirrhosis in a Predominantly African American Urban Population with Hepatitis C

Background: Statins are 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors which have the potential to modify HCV host cell lipid metabolism and thus could have an impact on outcomes of viral infection.

Published 25 May, 2018

Research Article

Trace Elements Status among Patients with Hepatocellular Carcinoma: A Case-Control Study

Background: Our research hypothesis is that copper, zinc, and selenium may have a potential role in the development of Hepatocellular Carcinoma (HCC).

Published 30 Mar, 2018

Research Article

Long-Term Acid Suppressive Therapy among Naïve Patients with Mycobacterium Tuberculosis Infection

Background/Aim: Our research hypothesis is that long-term acid suppression can lead to higher susceptibility to Mycobacterium tuberculosis infection due to defective gastric acid barrier.

Published 31 Mar, 2018

Research Article

Serum Wisteria floribunda Agglutinin Positive Mac-2-Binding Protein and Fib-4 Index on the Clinical Course of Patients with Chronic Hepatitis C Receiving Daclatasvir/Asunaprevir Therapy

Background/Aim: Serum Wisteria floribunda agglutinin positive Mac-2-Binding Protein (M2BPGi) is a noninvasive glycolytion-marker for fibrosis. In this study, we analyzed serial changes of fibrous markers during the clinical course of patients with chronic hepatitis C receiving daclatasvir/asunaprevir therapy.

Published 27 Nov, 2017


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