Shantata J Kudchadkar, Anil Rai and Jayesh Sagar*
Luton and Dunstable University Hospital, Luton, UKFulltext PDF
Abstract Mucosal Schwann Cell Hamartoma (MSCH) is one of the spindle cell neoplasms, which is relatively uncommon in Lower Gastrointestinal Tract (GIT). It is a newly recognized disease entity with no hereditary association, usually composed of bland spindle cells in lamina propria, showing S-100 positivity on immunohistochemical analysis. We present an unusual case of colonic mucosal Schwann cell hamartoma, in an asymptomatic elderly gentleman, detected incidentally at screening colonoscopy, along with a brief literature review. He underwent a thorough evaluation with contrast enhanced CT scan and Multidisciplinary Discussion (MDT) at our institution, following endoscopic polypectomy. Histopathology with immunohistochemistry confirmed the diagnosis of mucosal Schwann cell hamartoma. As MSCH is uncommon in colorectum & non-invasive in behavior, management and long-term follow-up is still under study. We aim to emphasize the significance of increased awareness required among the colorectal surgeons and pathologists, in order to differentiate it from other benign neural lesions of mesenchymal origin.
Mucosal Schwann Cell Hamartoma (MSCH); Spindle cell neoplasm; Neurofibromatosis; Polyp
Kudchadkar SJ, Rai A, Sagar J. A Rare Case of Mucosal Schwann Cell Hamartoma of Colonic Mucosa. Ann Clin Med Res. 2020; 1(2): 1006..