Ann Clin Diabetes Endocrinol | Volume 2, Issue 1 | Research Article | Open Access

Complete Androgen Insensitivity Syndrome (CAIS) and Karyotype 47, XXY, with Sertoli-Leydig Cell Tumor: Description of a Rare Case

Weber Silva DM^* and Bagatin de Souza Moreira B

Department of Endocrinology, University of the Region of Joinville – UNIVILLE, Brazil

^*Correspondance to: Weber Silva DM 

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Abstract

Objective: To report the rare case of a patient with Complete Androgen Insensitivity Syndrome (CAIS) with Klinefelter Syndrome (KS) (47, XXY) presenting a Sertoli/Leydig cell tumor discovered during the gonadectomy. Materials and Methods: Patient(s): Patient with 36 years-old seeking assistance with decreased libido. Intervention(s): Adequate hormone replacement therapy, which had not previously been instituted. Result: The patient had improved secondary sexual characteristics but only partially improved libido. Conclusion: The clinical case described shows a rare phenomenon such as the association between CAIS and KS, associated with the finding of Sertoli/Leydig cell tumor after gonadectomy

Keywords:

Androgen Insensitivity Syndrome; Klinefelter syndrome; Sertoli/Leydig cell tumor; Hormone Replacement therapy; Endocrinology

Citation:

Weber Silva DM, Bagatin de Souza Moreira B. Complete Androgen Insensitivity Syndrome (CAIS) and Karyotype 47, XXY, with Sertoli-Leydig Cell Tumor: Description of a Rare Case. Ann Clin Diabetes Endocrinol. 2019; 2(1): 1011.