Ann Clin Diabetes Endocrinol | Volume 2, Issue 1 | Case Report | Open Access

Fibrocalculous Pancreatic Diabetes (FCPD): Two Case Reports of FCPD Running in the Same Family. Can FCPD be Inherited?

Jaganmohan B^1*, Bairagi LJ¹, Rehman F¹, Silas MM¹, Jacinth M¹ and Ashok Jaiswal²

¹Department of Diabetology, Apollo Sugar Clinic, India
²Zydus Healthcare, India

^*Correspondance to: Jaganmohan B 

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Abstract

Background: Diabetes Mellitus (DM) is a global health burden leading to significant morbidity and mortality in both young as well as elderly individuals all over the world and there is a significant health care expenditure associated due to the complications caused by the disease. Although, Type-1 and Type-2 DM is the commonest forms of all diabetes, DM due to secondary causes has also been encountered in clinical settings. Fibrocalculous Pancreatic Diabetes (FCPD) is one of the unique and rare varieties of DM, secondary to chronic calcific pancreatitis. Chronic calculi resulting in inflammatory changes can affect both exocrine and endocrine part of pancreas which eventually results in FCPD. However the case studies available till date are mostly documenting individual case reports on FCPD without any evidence of genetic preponderance. But we would like to report two case studies of a middle aged man and his young adult daughter who are both affected by FCPD, probably indicating genetic role. Case Presentation Case 1: A 51 year old non-alcoholic South Indian Male presented with a history of chronic calcific pancreatitis 6 years ago. He later developed insulin dependent diabetes. Imaging of the abdomen, history and his clinical presentation corroborates with the criteria for diagnosing FCPD. Case 2: A 20 year old non-alcoholic girl, who is the daughter of the first case, also had a clinical presentation suggestive of FCPD and imaging of the abdomen revealed calculi in the pancreas which helped clinched the diagnosis

Citation:

Jaganmohan B, Bairagi LJ, Rehman F, Silas MM, Jacinth M, Jaiswal A. Fibrocalculous Pancreatic Diabetes (FCPD): Two Case Reports of FCPD Running in the Same Family. Can FCPD be Inherited? Ann Clin Diabetes Endocrinol. 2019; 2(1): 1009.