Ann Clin Case Rep | Volume 6, Issue 1 | Case Report | Open Access

CEUS in the Screening of Neuroendocrine Pancreatic Tumors

Adriana Gomotirceanu1*, Adina Sabau1, Aliz Tunyogi1, Florin Gomotirceanu1, Cristian Nicolae Chirila2, Paula Maria Chirila2 and Mirela Liana Gliga2

1Department of Internal Medicine and Ultrasonography, Topmed Medical Center, Romania
2“George Emil Palade” University of Medicine, Pharmacy, Science and Technology Targu Mures, Romania

*Correspondance to: Adriana Gomotirceanu 

Fulltext PDF


We present the case of a 53 years old female patient, who came in our department complaining of minor symptoms, accusing an atypical pain in the epigastric area. The abdominal ultrasound showed an intensely hypoechoic and well delimited solid mass located in the pancreatic head, measuring less than 2 cm. The lesion had the characteristics of a neuroendocrine tumor after contrast administration, with an intense enhancement during the arterial phase and a more rapid washout during the late phase compared to the rest of the parenchyma. The patient was addressed to an echo-endoscopy service where an ultrasound-guided fine needle biopsy was performed, with the pathology report confirming the diagnosis of a low grade neuroendocrine tumor. The next step was the surgical removal of the tumor (total enucleation). The patient was supervised by an oncologist for 2 years, through clinical exam, MRI, evaluation of serum markers and CEUS every 6 months. She is now declared cured.


Pancreatic neuroendocrine tumors; Contrast-Enhanced Ultrasound (CEUS)


Gomotirceanu A, Sabau A, Tunyogi A, Gomotirceanu F, Nicolae Chirila C, Maria Chirila P, et al. CEUS in the Screening of Neuroendocrine Pancreatic Tumors. Ann Clin Case Rep. 2021; 6: 2022..

Subscribe to Our Newsletter