Paulo Rodrigues* and Antonio Cavaleiro de Macedonia
Department of Urology, Hospital Santa Catarina de Sao Paulo, BrazilFulltext PDF
Introduction: PSA elevation regularly demands additional investigation to rule out Prostate Cancer (PCa). PIRADS has been added to understand the myriad of prostate pathologies allowing conservative management in selected cases. Case Report: A 71-year-old man who presented elevated PSA from 1.5 ng/ml to 13 ng/ml was investigated after mpMRI showed PIRADS-5 areas. Admittedly, rising PSA was due to urethral catheterization for BCG bladder instillation 3 weeks before. Persistent PSA elevation justified invasive investigation. Histology results of extended prostatic core-biopsies revealed diffuse granulomatous findings with no neoplastic lesions. Investigative tuberculosis exams were negative and PSA follow-up normalized to previous levels.
Rodrigues P, de Macedonia AC. Intravesical-BCG as an Unusual Cause of Elevated PSA Leading to an Elusive Diagnosis. Ann Clin Case Rep. 2021; 6: 2017..