Masafumi Aoki1, Sakurai Motoichirou1, Katsumi Mizuno1 *, Yuya Nakano1 , Hideyuki Asai1 and Keli M Hawthorne2
1Department of Pediatrics, Showa University School of Medicine, Tokyo, Japan 2Department of Pediatrics, University of Texas at Austin, USAFulltext PDF
Background: Several studies have confirmed the benefits of an exclusive human milk diet for premature infants; however, a donor human milk-based fortifier has not been available in Japan. Case Presentation: A donor human milk-based fortifier was recently used for the first time ever in Japan, given in conjunction with mother’s own milk to three premature infants. Details of these three infant case studies are reported here. These infants received the donor human milk-based fortifier as part of a rescue nutritional intervention due to poor weight gain in the presence of meconium ileus and perforation. Infants demonstrated good tolerance and weight gain while receiving the exclusive human milk diet. Conclusion: This is the first report of infants receiving an exclusive human milk diet in Japan, consisting of mother’s own milk with a donor human milk-based fortifier for additional calories and nutrients. Infants demonstrated good tolerance and experienced improved weight gain while receiving the product.
Human milk; Donor human milk; Premature infant; Preterm infant
Aoki M, Motoichirou S, Mizuno K, Nakano Y, Asai H, Hawthorne KM. First Use in Japan of Exclusive Human Milk Diet: Case Report Series. Ann Clin Case Rep. 2020; 5: 1877.