Donald Roshan, Kelly Shortridge* and Rob Schuster
Department of General Surgery, Midwestern University, USAFulltext PDF
In patients with non-functioning pancreatic neuroendocrine tumors, surgical resection is a viable option for many. Although rare, the general surgeon should be familiar with the workup, evaluation and treatment of these tumors. PNETs account for 1% of all pancreatic tumors, the majority of which are non-functional. The location variation of these can be significant making surgical planning challenging. Although PNETs can occur sporadically, they have been found to be associated with MEN-1, Von Hippel-Lindau, and neurofibromatosis type 1. PNETs, also called Islet cell tumors, are pancreatic neoplasms that are derived from islet cells within the pancreas. Non-functioning PNETs are typically found incidentally on imaging. However, patients with larger PNETs may present with abdominal pain, mass effect, obstructive symptoms, or metastatic disease. Surgical resection in these patients can be curative or palliative.
Roshan D, Shortridge K, Schuster R. A Case of a Large Non-Functional Pancreatic Neuroendocrine Tumor: A Case Report and a Review of the Literature. Ann Clin Case Rep. 2020; 5: 1861.