Ann Clin Case Rep | Volume 5, Issue 1 | Case Report | Open Access

Acute Viral Encephalitis Associated with SARS-CoV-2

Zandifar S1* and Zandifar Z2

1Department of Neurology, Alborz Universirty of Medical Sciences, Iran 2Department of Otolaryngology, Alborz Universirty of Medical Sciences, Iran

*Correspondance to: Sepideh Zandifar 

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Encephalitis is an inflammation of the brain parenchyma caused by either viruses or bacteria. The viruses can broadly cause central nervous system infections. As the viral encephalitis with severe complications can be life-threatening it has raised global concerns. Depending on the pathogen, host immunity and the environment in which patient live, the expansion of brain involvement and prognosis of this disease would be different. Coronaviruses are pathogens that typically involve respiratory and gastrointestinal system. Although rare, the novel coronavirus (COVID-19) can probably involve central nervous system and cause neurological symptoms such as headache, seizure, myopathy and impaired consciousness. The viral neurotropic and neuroinvasive characteristics of some coronaviruses facilitate accessing the nervous system through nasal cavity and cause some neurological disorders like encephalitis, demyelination and neurodegeneration disorders. Here we present two cases that according their history, manifestations and laboratory data confirmed COVID-19 followed fatal viral encephalitis.


Coronavirus; COVID-19, Encephalitis; SARS-CoV; Covid; Coronavirus disease 2019


Zandifar S, Zandifar Z. Acute Viral Encephalitis Associated with SARSCoV- 2. Ann Clin Case Rep. 2020; 5: 1845..

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