Department of Family and Community Medicine, Texas Tech University Health Science Center El Paso, USAFulltext PDF
Acute onset and worsening of knee pain may be related to various pathology. Such findings in a young to middle aged male should raise suspicion for a more conspicuous disease other than osteoarthritis. Obtaining a thorough history and physical will provide valuable insight into the potential etiology of such acute knee pain. Benign vs. malignant conditions could be the source of such complaints. It is important that a thorough evaluation, including imaging, be completed to rule out malignant and/or traumatic injuries. Patients with a history of malignancy should raise significant concern and lead to further evaluation. Bone malignancies such as chondrosarcoma are rare, but aggressive malignancies. Knee pain should never be attributed to osteoarthritis in a middle aged man with a history of malignancy and rapidly progressive complaints.
Murphy D. When Knee Pain Isn′t Just Arthritis. Ann Clin Case Rep. 2019; 4: 1629.