Alejandro Perez1*, Sarah Findeis2, Atin Agarwal2, Julia Berry2 and Katie King2
1Department of Pathology, Texas A&M University College of Medicine, USA
2Department of Pathology, Baylor University Medical Center, USA
Cribriform-Morular Variant of Papillary Thyroid Carcinoma (CMV-PTC) is an uncommon variant of Papillary Thyroid Carcinoma (PTC). CMV-PTC can be associated with Familial Adenomatous Polyposis (FAP), an autosomal dominant polyposis syndrome caused by a mutation in the APC gene which leads to a disruption of the Wnt/β-catenin pathway. Understanding the relationship between CMV-PTC and FAP is a diagnostic tool not only for pathologists, but also for clinicians as FAP has several implications for not only the patient, but the patient's family as well.
Perez A, Findeis S, Agarwal A, Berry J, King K. Cribriform-Morular Variant of Papillary Thyroid Carcinoma: Two Cases of a Rare Thyroid Cancer Associated with Familial Adenomatous Polyposis. Ann Clin Case Rep. 2019; 4: 1612.