Ann Clin Case Rep | Volume 4, Issue 1 | Case Report | Open Access

Ganglioneuroblastoma: Spinal with Thoracic Extension- A Rare Diagnosis

Ashwarya Aditya Mehra1, Uday Singh Raswan1* and Rahul Mannan2

1Department of Neurosurgery, Amandeep Hospital, India
2Department of Pathology, Amandeep Hospital, India

*Correspondance to: Uday Singh Raswan 

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Background: Ganglioneuroblastoma are rare tumors with origin from the neural crest cell. Spine is very rare site for their occurrence. In the spinal canal, the most common location is thoracic, intramedullary site. Our case is significant because it was located in the thoracic spine extending extradurally into the thoracic cavity, first reported in the literature.Case
Presentation: We report a 13-year old female admitted with paraplegia and urinary retention. Sensations were lost below D8 level. Magnetic resonance imaging showed an irregular enhancing lesion in extradural location from D4-D9 vertebra with intrathoracic extension on right side. Laminectomy (D5-D9) and right rib resection (rib 7 and 8) was done. Subtotal excision of the thoracic mass was achieved. D5,6-D9,10 right transpedicular fixation was done. Adjuvant radiotherapy was advised. After 8 months of follow up, the patient’ power in both lower limbs was grade 2.Conclusion: Ganglioneuroblastoma in children and young adults should be included in the differential diagnosis of thoracic cord tumors. Definitive diagnosis depends on post-operative histological examination. Curative treatment should be a complete resection of the tumor. Also, in partially resected cases, adjuvant radiotherapy may become necessary, along with close follow up.


Ganglioneuroblastoma; Spinal; Thoracic


Mehra AA, Raswan US, Mannan R. Ganglioneuroblastoma: Spinal with Thoracic Extension- A Rare Diagnosis. Ann Clin Case Rep. 2019; 4: 1572.

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