Ann Cardiovasc Surg | Volume 5, Issue 1 | Case Report | Open Access
Shun Hiraga*, Yoshihiro Hayata, Tomoaki Hirose, Ryohei Fukuba, Junichi Takemura, Rei Tonomura, Sayaka Tamada, Kazuhiro Mitani, Masaya Hanalawa and Shinya Yokoyama
Department of Thoracic and Cardiovascular Surgery, Nara Medical University, Japan
*Correspondance to: Shun Hiraga
Fulltext PDFHeyde’s syndrome is defined as a combination of aortic stenosis and recurrent gastrointestinal bleeding from angiodysplasia; it is recently known as von Willebrand disease type 2A, with loss of a large multimer of von Willebrand factor. We report a successfully treated case of Heyde’s syndrome with intestinal bleeding and angiodysplasia. An 87-year-old man presented with recurrent gastrointestinal bleeding and advanced anemia. Angiodysplasia was observed in the intestine on capsule endoscopy; the diagnosis was Heyde’s syndrome. Gel electrophoresis revealed the loss of large multimer of von Willebrand factor. We performed aortic valve replacement. After the operation, the large multimer of von Willebrand factor decreased in the early phase, then increased, and finally normalized. We report a case of successful aortic valve replacement for Heyde’s syndrome with evaluation of the multimer of von Willebrand factor in the perioperative period.
Hiraga S, Hayata Y, Hirose T, Fukuba R, Takemura J, Tonomura R, et al. A Case of Successful Aortic Valve Replacement for Heyde’s Syndrome with Perioperative Evaluation of Multimer of Von Willebrand Factor. Ann Cardiovasc Surg. 2022;5(1):1031..