Ann Atheroscler Res | Volume 1, Issue 1 | Research Article | Open Access
Nasir Sivri1, Mesut Ozdemir2, Kenan Yalta1, Kubilay Senen1 and Ertan Yetkin3*
1Department of Cardiology, Trakya University, Turkey
2Department of Cardiology, Abant Izzet Baysal University, Turkey
3Department of Cardiology, Yenisehir Hospital, Turkey
*Correspondance to: Ertan Yetkin
Fulltext PDFBackground: Coronary collateral vessel development (CCV) is an adaptive response of the coronary vascular system to arterial occlusion and one of the most important mechanisms to salvage myocardium at risk. During the early phase of acute myocardial infarction (AMI), patients will show marked angiographic heterogeneity in collateral formation that is independent of the status of coronary artery occlusion. In our study we aimed to assess presence and confounders of CCV in the early setting of myocardial infarction with ST elevation (STEMI) in patients undergoing percutaneous coronary intervention.
Materials and Methods: Collateral artery grading was performed by using Cohen-Rentrop method to the culprit vessel with total occlusion. Patients with grade 0 collateral development were regarded as absence of collateral vessels and patients with grade 1, 2 or 3 collateral development were regarded as presence of collateral vessels. Age, gender, DM, hypertension, hyperlipidemia, smoking, pain-PCI time, family history of coronary artery disease, patients’ medications, systolic blood pressure, were included in regression analysis.
Results: There were not statistically significant differences in terms of Diabetes Mellitus, hypertension, smoking, family history of coronary artery disease, gender, medications (nitrates, beta blockers, antiplatelets, renin-angiotensin system blockers, and statin).
Conclusion: We have not documented any parameters associated with development of CCV in the setting STEMI. Beyond the clinical or environmental factors contributing to formation of collateral vessel development, some patients seem to be unlucky or genetically are not prone to have a pre-existed arteriolar connection.
Atherogenesis; Coronary artery disease; Coronary collateral blood flow; Collateral circulation; Collateral development
Sivri N, Ozdemir M, Yalta K, Senen K, Yetkin E. Predictors of Coronary Collateral Vessels at the Time of Primary Percutaneous Intervention: Is there any? Ann Atheroscler Res. 2018;1(1):1002.