Ann Arthritis Clin Rheumatol | Volume 1, Issue 1 | Research Article | Open Access

Real-time PCR of Mycoplasma pneumoniae in Synovial Fluid of Rheumatoid Arthritis and Osteoarthritis Patients

Maryam Sahebari¹, Amir Hossein Heidari¹, Maryam Rastin² and Kamila Hashemzadeh^1*

¹Rheumatic Disease Research Center, Mashhad University of Medical Sciences, Iran
²Immunology Research Center, Mashhad University of Medical Sciences, Iran

^*Correspondance to: Kamila Hashemzadeh 

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Abstract

Objective: The present study aims to explicate the role of Mycoplasma pneumoniae (M. pneumoniae) in RA pathogenesis by detecting its species-specific DNA in patients’ synovial fluid.
Methods: The 100 patients with RA and 100 patients with knee Osteoarthritis (OA) were recruited. Knee synovial fluid of participants was analyzed for M. pneumoniae by real-time PCR.
Results: M. pneumoniae was only detected in two percent of RA patients’ and 1% of OA patient's synovial fluid (p=1.000).
Conclusion: Our result shows a weak possibility of the role of M. pneumoniae in RA pathogenesis

Keywords:

Mycoplasma pneumoniae; Osteoarthritis; Real-time PCR; Rheumatoid arthritis

Citation:

Sahebari M, Heidari AH, Rastin M, Hashemzadeh K. Real-time PCR of Mycoplasma pneumoniae in Synovial Fluid of Rheumatoid Arthritis and Osteoarthritis Patients. Ann Arthritis Clin Rheumatol. 2018; 1(1): 1005.