Am J Pharmacol | Volume 2, Issue 3 | Review Article | Open Access

The Story of Julius Axelrod (1912-2004): A Testament to Commitment

Ronald PR*

Department of Pharmacology and Toxicology, University at Buffalo, USA

*Correspondance to: Ronald PR 

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The key research of Julius Axelrod focused on the release, reuptake and storage of the neurotransmitters norepinephrine and epinephrine. These discoveries provided a new model for understanding the metabolism and regulation of neurotransmitters. In elucidating how neurotransmitters transmit their specific messages, Axelrod not only revolutionized research in catecholamine metabolism, but ultimately fostered the development of therapies for mental illness and pain relief. In 1970 Julius Axelrod was awarded the Nobel Prize in Physiology or Medicine for discoveries related to the mechanisms involved in the storage, release, and inactivation of neurotransmitters.


Ronald PR. The Story of Julius Axelrod (1912-2004): A Testament to Commitment. Am J Pharmacol. 2019; 2(3): 1023.

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