Am J Pharmacol | Volume 2, Issue 1 | Research Article | Open Access

A Study based on Prescribing Pattern of Antibiotics in Hospital Acquired Infections of Tertiary Care Hospital

Riya Johnson, Jaidev Kumar*, Sumana and Abdu Rashid

Department of Pharmacy, JSS Academy of Higher Education and Research, India

*Correspondance to: Jaidev Kumar 

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Abstract

Introduction: According to World Health Organization (WHO), nosocomial infection, also called “hospital acquired infection” can be defined as: An infection acquired in hospital by a patient who was admitted for a reason other than that for the infection. It is an infection occurring in a patient during hospital stay or other health care facility in which the infection was not present or incubating at the time of admission As far the knowledge of research investigators there are only few research studies were carried out with respect to rational use of antibiotic in hospital acquired infections, but according to epidemiology the microbiological sensitivity pattern can differ from one region to another region. Therefore to understand the sensitivity pattern and resistance of antibiotics, the prescribing pattern of antibiotic should be studied to know how antibiotics is prescribed in according to specific hospital acquired infections prevailing in tertiary care hospital.
Objective: To study the prescribing pattern of antibiotics for hospital acquired infections.
Methods: This was a prospective observational study conducted in Surgery, Neurosurgery and Critical Care units of JSS Hospital, Mysore which is an 1800 bed multi-specialty tertiary care teaching hospital. Patients who met study criteria were enrolled in this research study. This study was conducted over a period of six months. The enrolled patients were monitored on daily basis. The therapy related data such as name of the antibiotic which was identified using ATC code, brand name, dose, route, frequency, dosage adjustment in case of renal insufficiency, cost of the drug, duration of the therapy and choice of antibiotic after culture sensitivity report were collected and documented to determine the prescribing pattern of antibiotic. Results and
Discussion: The most frequently prescribed antibiotic was Cefoperazone + Sulbactum (42%) followed by Linezolid (36%), Piperacillin + Tazobactum (32%), Colistin (32%) and Imipenem (24%).
Conclusion: This research study concludes that more irrational use of antibiotic was observed in hospital acquired infections which had resulted increased health care cost of the patient as well as antibiotic resistance. The average duration of prescribed antibiotic in our research study for Cefoperazone + Sulbactum was 8.8 days followed by Linezolid 6.2 days, Piperacillin + Tazobactum 8.8 days + 4 days, Colistin 8.6 days and Imipenem BD for 8 days and TID for 9.5 days.

Keywords:

Antibiotic; Hospital; Acquired; Infection

Citation:

Johnson R, Kumar J, Sumana, Rashid A. A Study based on Prescribing Pattern of Antibiotics in Hospital Acquired Infections of Tertiary Care Hospital. Am J Pharmacol. 2019;2(1):1011.

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