Am J Pharmacol | Volume 1, Issue 1 | Research Article | Open Access
Jahanara Laizu1, Roksana Parvin2, Nasrin Sultana3, Matia Ahmed4, Rayhana Sharmin1, Zinat Rehana Sharmin1 and Abu Syed Md Mosaddek1*
1Department of Pharmacology, Uttara Adhunik Medical College, Bangladesh
2Department of Pharmacology, Medical College for women and hospital, Bangladesh
3Department of Community Medicine, Shaheed Tajuddin Ahmed Medical College, Bangladesh
4Department of Physiology, Uttara Adhunik Medical College, Bangladesh
*Correspondance to: Abu Syed Md Mosaddek
Fulltext PDFBackground: Antibiotic prescribing practice by physicians has abruptly increased globally due to increase in antibiotic usage and prevalence of drug resistances. Rational prescribing is mandatory to reduce drug resistance. Rationality analysis of prescribing drugs can help to point towards irrationality and can make a consensus among physicians for rational prescribing.
Objectives: The aim is to evaluate the pattern of antibiotic prescribing based on rationality, their usages in various disease conditions among different level of private practitioners in Dhaka city.
Methods: This observational study was carried out with a self-designed standard questionnaire by manual data collection over a 24 months period (01.01.2016 to 31.12.2017).The data were collected from the patient’s prescription and directly interviewing the patients who were prescribed at least one antibiotic during the study period. WHO/INRUD prescribing indicators were used and descriptive statistics were applied to the collected data and analyzed using Microsoft Excel software.
Results: A total of 2,000 prescriptions were analyzed during the study period. Extreme aged patients were prescribed more antibiotics. Commonly prescribed antibiotic groups were cephalosporin (36.00%), macrolides (25.50%), quinolones (21.00%), penicillins (7.50%), and metronidazole (10.00%). 55.25% prescriptions had complete information on dosage form, 65% had complete direction for antibiotics use and 66.5% patients were completed full course of antibiotics. Although 81% prescriptions have no clinical test for using antibiotics, even though the percentages of patients disease recovery were 66% and incompliance were 34%.
Conclusion: The study pointed a need for national guidelines for the treatment of common diseases to maintain rationality in prescribing antimicrobial agents and a large surveillance on antimicrobial prescribing appropriateness is warranted.
Antimicrobial prescribing; Rationality; Surveillance
Laizu J, Parvin R, Sultana N, Ahmed M, Sharmin R, Sharmin ZR, et al. Prescribing Practice of Antibiotics for Outpatients in Bangladesh: Rationality Analysis. Am J Pharmacol. 2018;1(1):1008.