Am J Otolaryngol Head Neck Surg | Volume 5, Issue 10 | Short Communication | Open Access

Non-Differential Microbial Community Composition in Nasal Polyps from Asosmic vs. Normosmic CRSwNP Patients

Zhou MZ^1,2, Zhong C^1,2#, Hu Y^1,2, Wang L^1,2, Cheng L^1,2, An J1,2, Chen Z^1,2* and Liu B^1,2*

¹Department of Otolaryngology Head and Neck Surgery, XuZhou Central Hospital, China
²XuZhou Clinical School of Xuzhou Medical University, XuZhou, China
^#This author contributed equally to this work

^*Correspondance to: Zhilan Chen 

Fulltext PDF

Abstract

Nasal polyposis is one of the most globally distributed life-disturbing disease. In patients of Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP) presenting for surgical treatment, 90% suffered from anosmia/hyposmia. Wondering whether the microbiome in nasal polyps of CRSwNP patients related, we studied the microbial community composition in nasal polyps of dysosmic vs. normosmic CRSwNP patients by bacterial 16S rRNA gene sequencing. Results showed no strong separation of grouped samples, which suggested that microbial community composition in nasal polyps might not be an active direction for future study.

Keywords:

Nasal polyps; Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP); Microbial community composition; Anosmia; Hyposmia

Citation:

Zhou MZ, Zhong C, Hu Y, Wang L, Cheng L, An J, et al. Non-Differential Microbial Community Composition in Nasal Polyps from Asosmic vs. Normosmic CRSwNP Patients. Am J Otolaryngol Head Neck Surg. 2022; 5(10): 1213.