Review Article

Synthesis, Characterization and Structure Activity Relationship (SAR) Studies of Differently Substituted Naphthalene and Triazine Incorporated Heterocyclic Molecule as Possible Anti-Bacterial and Anti-Fungal Agents

Nitrogen heterocyclic compound play an important role in medicinal chemistry due to their biological activities towards microorganisms.

Published 25 Sep, 2018


Research Article

Acinetobacter Baumannii Antibiotic Multiresistance Evolution in Hospital Acquired Infections, Clinical Data from a Six Year Study in Mexico

Introduction: As T. Dobzhansky said, since “nothing in biology makes sense except in the light of evolution”, the increasing diseases and deaths caused by hospital acquired infections by multiresistant germs such as Acinetobacter baumannii cannot be understand or fought efficiently without an evolutionary approach.

Published 18 Jul, 2018


Review Article

Review on Combinatorial Approach for Inhibiting Candida albicans Biofilm

C. albicans has the ability to form biofilms on biotic and abiotic surfaces. Biofilms are highly resistant to various antifungal drugs and there are complex mechanisms underlying biofilm resistance.

Published 23 Jun, 2018


Clinical Image

Disseminated Emboli caused by a Large Vegetation in Staphylococcus aureus Endocarditis

A 59-year-old woman with no prior medical history presented with acute fever and generalized weakness.

Published 22 Jun, 2018


Research Article

Analysis of Mycobacterium tuberculosis Drug Susceptibility to Extended Spectrum β - Lactam Antibiotics by Nitrate Reductase Assay

Background and Objectives: ESBLs are the lactam antibiotics hydrolyzing enzymes playing major barriers in employing lactam antibiotics to treat TB infection.

Published 22 Jun, 2018


Editorial

Listeria; A Potential Risk for Food Safety and Public Health

Listeria monocytogenesis a well-known food borne pathogen and cause one of the most serious and life threatening disease, listeriosis.

Published 11 Jun, 2018


Mini Review

Immunological Response of Recombinant Vaccinia Virus Including the HIV-1 Gene

We examined mouse immune response to 4 kinds of recombinant vaccinia viruses carrying the human immunodeficiency virus type 1(HIV-1) Group-specific Antigen(gag) gene, including vacgag/pol, which produces HIV-1-like particles with processed gag proteins; vac-gag, which also produces HIV-1-like particles but with unprocessed gag protein; and vac-gag-pol-fuse and vaces-gag/pol, neither of which produces such virus particles but releases Reverse Transcriptase (RT) and gag protein, respectively, from infected cells. Although infection of mice with recombinant vaccinia viruses induced production of the anti-HIV-1 gag protein 24 (p24) antibodies in all mice, vac-gag/pol and vac-es-pol induced higher production than the other two recombinants.

Published 03 May, 2018


Review Article

Properties of Candida albicans Biofilms: An Update

Biofilm formation in Candida albicans is one of the important virulence factors causing infections refractory to antimicrobial agents.

Published 01 May, 2018


Research Article

Complicated Major Labia Abscess - Clinical Manifestation and Microbiology of Hospitalized Women

Background: Women hospitalized with complicated Non-Bartholin major labia abscesses an uncommon insufficient investigated entity.

Published 01 May, 2018


Review Article

Serological Diagnosis of Canine Visceral Leishmaniasis

Canine Visceral Leishmaniasis (CVL) is an infection of veterinary importance, involving a complex interaction between trypanosomatid protozoa of the Leishmania donovani complex, sand fly vectors, environmental conditions that influence the distribution of the vector, dogs that are the major urban reservoirs and humans that are hosts that harbor these parasites.

Published 11 Apr, 2018


Research Article

Susceptibility of Clinical Isolates of Staphylococcus aureus to Alpha-Melanocyte Stimulating Hormone and Its In Vivo Efficacy

Antimicrobial Peptides (AMPs) are one of the most promising future strategies for defeating the antibiotic resistance.

Published 11 Apr, 2018


Research Article

Tobacco Extract Induces Yeast to Hyphal form Transition in the Human Pathogen, Candida albicans

Candida albicans is a commensal microorganism which lives in the oral, digestive and genitourinary tracts.

Published 09 Apr, 2018


Mini Review

IgG Avidity Test to Discriminate between Acute and Chronic Toxoplasmosis

Marine environment is acquiring even more interest as a source of new bioactive compounds, among these marine organism’s derived bioactive peptides are considered a promising group of natural substances exhibiting different biological activities: antimicrobial, anticancer, antihypertensive, antiinflammatory and so on.

Published 06 Apr, 2018


Research Article

Antimicrobial Susceptibility and Biofilm Production by Staphylococcus aureus and Staphylococcus epidermidis Isolated from Elderly Residents of a Nursing Home

Elderly residents of nursing homes are more susceptible to bacterial infections when compared to young adults, mostly by commensal bacteria from microbiota, such as staphylococci.

Published 05 Apr, 2018


Review Article

Therapeutic and Biotechnological Importance of Bacterial Vesicles and their Inhibitors

Bacteria are unicellular organisms. But instead of living independently, each bacterial cell lives as a member of a society.

Published 04 Apr, 2018


Review Article

Synergistic Activation of Doxorubicin against Cancer: A Review

Doxorubicin is an anthracyline drug extracted from Streptomyces peucetius and used in the treatment of several cancers including breast, lung and ovarian cancers.

Published 04 Apr, 2018


Research Article

Muscarinic Acetylcholine Receptor Agonists and Antagonists Regulate Yeast to Hyphal form Transition in Candida albicans

Reversible transition from yeast to hypha in Candida albicans represents a good model system for studying cell differentiation.

Published 02 Apr, 2018


Research Article

The Impact of Methicillin-Resistant Staphylococcus aureus (MRSA) Decolonization Protocols on its Mupirocin and Chlorhexidine Susceptibility

Development of bacterial resistance to the antibiotics constituted a major health problem.

Published 28 Mar, 2018


Review Article

Antimicrobial Peptides Derived from Marine Sponges

Marine environment is acquiring even more interest as a source of new bioactive compounds, among these marine organism’s derived bioactive peptides are considered a promising group of natural substances exhibiting different biological activities: antimicrobial, anticancer, antihypertensive, antiinflammatory and so on.

Published 12 Mar, 2018


Review Article

Role of Natural Products against Microorganisms

Since antiquity, man has used plants to treat common infectious diseases and some of these traditional medicines are still included as part of the habitual treatment of various maladies.

Published 07 Feb, 2018


Research Article

Isolation and Morphological Characterization of New Bacteriophages Active against Campylobacter jejuni

Campylobacter jejuni (C. jejuni) is a food borne pathogen that causes gastroenteritis worldwide and neurological diseases in humans.

Published 16 Jan, 2018


Research Article

Heptaplex Real-Time Polimerase Chain Reaction for Neonate Sepsis Pathogens in Brazil

This work has as its main objective the development of a more comprehensive molecular diagnostic method, efficient to diagnose crucial agents in early neonatal bacterial sepsis (ENS), in order to elaborate a rational and specific therapy.

Published 08 Feb, 2018


Research Article

RP-HPLC Method Development and Method Validation of Lopinavir and Ritonavir in Pharmaceutical Dosage Form

An Accurate, Precise, Rugged, Reproducible Reverse Phase High Pressure Liquid Chromatographic (RP-HPLC) method has been developed and validated for the simultaneous estimation of Lopinavir and Ritonavir in pharmaceutical dosage form of anti-retroviral protease inhibitor class of compounds.

Published 10 Jan, 2018


Short Communication

Virulotypes of Uropathogenic E. Coli Isolates from Diabetic Patients in Tunisia: Occurrence of the Invasion-Associated IbeA Gene

Extraintestinal pathogenic Escherichia coli (ExPEC) are an important cause of urinary tract infections (Uropathogenic E. coli, UPEC), neonatal meningitis and septicemia (neonatal meningitis E. coli, MNEC) in humans [1].

Published 22 Jan, 2018





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