Am J Clin Microbiol Antimicrob | Volume 1, Issue 3 | Mini Review | Open Access
Maria Elizabeth Marquez Contreras*
Department of Biology, Parasite Enzymology Laboratory, University of the Andes, Merida, Venezuela
*Correspondance to: Maria Elizabeth Marquez Contreras
Fulltext PDFSerodiagnosis of toxoplasmosis is usually achieved by the detection of IgG and IgM against Toxoplasma gondii. Routinely the detection of IgM antibodies is an acute phase indicator, but in the case of this disease, this isotype can persist even after years of this initial phase of infection, which represents many disadvantages during the diagnosis early of the congenital transmission, that occurs when an infected pregnant woman transmits the parasite to her unborn baby. Numerous researchers have conducted studies to detect recent infections that arise in an unapparent way, without clinical symptoms (asymptomatic), in newborns or fetus infected by congenital route, which due to the lack of administration of a rapid and timely chemotherapeutic treatment can present severe pathological damages, and even, trigger in the death. Serological tests can present difficulties in differentiating acute cases of chronic infections. The IgG avidity test has been developed to distinguish between latent acute and infections in pregnant women who present a mixture of IgG isotypes and IgM anti-T. gondii. It is an important additional tool that saves time and money in the diagnosis of infections in women during pregnancy, as well as favors an accurat
Contreras MEM. IgG Avidity Test to Discriminate between Acute and Chronic Toxoplasmosis. Am J Clin Microbiol Antimicrob. 2018; 1(3): 1012.