Am J Clin Microbiol Antimicrob | Volume 1, Issue 2 | Review Article | Open Access

Synergistic Activation of Doxorubicin against Cancer: A Review

Wakharde AA, Awad AH, Bhagat A and Karuppayil SM^*

Wakharde AA, Awad AH, Bhagat A and Karuppayil SM* School of Life Sciences, SRTM University, India

^*Correspondance to: Sankunny Mohan Karuppayil 

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Abstract

Doxorubicin is an anthracyline drug extracted from Streptomyces peucetius and used in the treatment of several cancers including breast, lung and ovarian cancers .A major limitation for the use of doxorubicin is cardiotoxicity, patients need to more possible to achieve efficacy at lower doses with lesser toxicity for this phytochemicals which occur in many vegetables, plants and fruits frequently consumed by humans, it shows antimicrobial and anticancer activity. These findings suggest that doxorubicin and phytochemicals combination may be most effective in cancer chemo preventative therapy.

Citation:

Wakharde AA, Awad AH, Bhagat A, Karuppayil SM. Synergistic Activation of Doxorubicin against Cancer: A Review. Am J Clin Microbiol Antimicrob. 2018; 1(2): 1009.